17α-Hydroxyprogesterone CAS 68-96-2

Hordhac 17 α- Hydroxyprogesterone, oo mararka qaarkood loo yaqaan Hydroxyprogesterone (Ingiriis: hydroxyprogesterone, OHP), waa steroid progesterone endogenous ah oo la mid ah progesterone, waana horudhaca biosynthesis ee hoormoonno badan oo steroid endogenous ah, oo ay ku jiraan androgen, estrogen, glucocorticoid, mineralocorticoid iyo qaar ka mid ah neurosteroids. Bioactive 17-Hydroxyprogesterone (17-OHP) waa progesterone endogenous ah iyo dhexdhexaad kiimiko ah oo ku jira biosynthesis-ka hoormoonnada kale ee steroid. Daraasadaha In vitro 17 α- OHP waa progesterone sida chemobookin receptor agonist, inkastoo saameynteedu ay tahay mid daciif ah. Sidoo kale waa dhexdhexaad kiimiko ah oo ku jira biosynthesis-ka hoormoonnada steroid sida androgens, estrogen, hoormoonnada galmada, glucocorticoids, iyo mineralocorticoids. Daraasadda In vivo 17 Hydroxyprogesterone waa soo-saare steroid oo wax ku ool ah oo loogu talagalay GVBD (jeexitaanka vesicle taranka). Astaamaha kiimikada ee crystallization (acetone/hexane). Barta dhalaalka 221 ℃ (219-220 ℃). [ α ] 20/D+97 ° (chlorofor